Cementoossifying fibromas cofs are benign lesions affecting the jaws. They commonly affect adult females between the third and fourth decade of life, predominantly occurring in the premolarmolar region of the mandible. In early stage it appears as unilocular, welldefined radiolucency. It is most commonly seen between the third and fourth decades of life 26, and is more frequent in women than in. Lowgrade osteosarcoma arising from cementoossifying fibroma. The term cementifying fibroma was originally applied to the lesion of the mandibular incisor teeth now referred to as periapical cemental dysplasia pindborg. Cementoossifying fibroma cof is considered by most as relatively rare, benign. Massive ossifying british journal of ophthalmology. Juvenile ossifying fibroma of the mandible journal of oral. First description of ossifying fibroma was given by menzel in 1872 while the term was given by montgomery in 1927. Cementoossifying fibroma is a benign growth, considered to originate from the periodontal ligament.
Peripheral cemento ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. To our knowledge, this is the first case of a cementoossifying fibroma in this location. A 72yearold patient was referred for a subclinical lesion of the mandible. Apr 19, 2011 cemento ossifying fibroma cof is considered a benign osseous tumour, very closely related to other lesions such as fibrous dysplasia, cementifying periapical dysplasia or amentoosseous dysplasia.
Most of the lesions typically show slow and often expansile growth. Cementoossifying fibroma cof is a well demarcated and encapsulated neoplasm that contains fibrous tissue and varying amounts of. Cemento ossifying fibroma cof is a benign odontogenic tumor which is believed to be derived from periodontal ligament cells. Juvenile ossifying fibroma is a rare, benign fibroosseous tumour. Florid cemento osseous dysplasia gigantiform and familial multiple cementoma iii. Central cemento ossifying fibroma is a fibroosseous lesion causing slow expansion of the involved bone and is usually manifested after attaining significant growth. Ct scan findings revealed a bony expansion due to a huge multiloculated mass with varying density figure 3. A case report of cementoossifying fibroma springerlink. Diagnostic pathology two cases of multiple ossifying fibromas in the jaws tingting wang 1 ran zhang 0 lin wang 1 yan chen 0 qing dong 1 tiejun li 0 2 3 0 department of oral pathology, peking university school and hospital of stomatology, 22 south zhongguancun avenue, haidian district, beijing 81, pr china 1 department of oral medicine, hebei united university, school and hospital of. Fujimoto y, katoh m, miyata m, kawai t, saito k, morita m. They most often arise from the tooth bearing areas of these bones. It is a bony tumour of the maxilla of possibly odontogenic origin with aggressive behavior and high tendency for recurrence. Cemento ossifying fibroma cof is considered by most as relatively rare, benign, nonodontogenic neoplasm of the jaw bones and other.
Ossifying fibroma definition of ossifying fibroma by. It comprises fibrous tissue containing a variable quantity of mineralized material resembling bone andor cement, whence the term cementoossifying. Pdf aggressive cementoossifying fibroma of the jaws. Psammomatoid ossifying fibroma jama ophthalmology jama. Mar 30, 2020 an ossifying fibroma is typically treated by surgical removal. Department of oral medicine, diagnosis and radiology, k. Peripheral cemento ossifying fibroma a case report with. The 1992 who classification groups it under a simple designation cof with two histologic types, cementifying fibroma and ossifying fibroma, that.
Cemento ossifying fibroma is a slowgrowing lesion most commonly seen in women during the third and fourth decades of life. Ossifying fibromas are benign bone lesions that should be differentiated from non ossifying fibromas and fibrous dysplasia. They are common growths seen in the oral cavity presenting as different pathological entities such as irritational fibroma, odontofenic fibroma, central and peripheral ossifying fibroma. Cementoossifying fibroma a case report omics international. Osteofibrous dysplasia is considered as a separate pathological entity in view of its different presentation and treatment, although histopathologically similar to ossifying fibroma. Cementoossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cementoossifying fibroma. It is relatively common in mandible but rare in maxilla. Sep 22, 2010 the concept of fibroosseous lesions of bone evolved over the last several decades to include two major entities.
Ossifying fibroma of is benign bone lesions, most frequent in young children, more common in the maxillary sinus and mandible 7589%, the pathogenesis of the tumor is not clear, there are many subtypes of of. We described a case of central cementoossifying fibroma involving the right mandible of a thirtyfivefemale patient by presenting its clinical, radiographic, and. The cementoossifying fibroma cof is a mesodermal, nonodontogenic tumour of ectopic multipotential periodontal membrane blast cells. Cementoossifying fibroma cof are rare, benign neoplasms that usually arise from the mandible or maxilla. Cementoossifying fibromas are rare fibroosseous benign neoplasms that affect the jaws. Florid cementoosseous dysplasia mixed fibrous dysplasia mixed cementoossifying fibroma 2nd stage paget disease mixed osteogenic sarcoma mixed chondrosarcoma mixed metastatic tumors mixed osteoradionecrosis mixed. Cementoossifying fibroma more c, thakkar k, asrani m indian j. The cemento ossifying fibroma cof is a mesodermal, nonodontogenic tumour of ectopic multipotential periodontal membrane blast cells. Cementoossifying fibroma is a benign fibroosseous maxillary tumor. It was first described as relatively uncommon, solitary, nonneoplastic gingival growth by eversol and robin. Psammomatoid ossifying fibroma pof is characterized histologically by numerous small round ossicles resembling psammoma bodies and is a locally invasive lesion of facial and cranial bones. Jan 14, 20 the concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities. A 72yearold patient was referred for a subclinical lesion of the. Even when the fibroma has been cut out surgically, the growth will sometimes recur.
Ossifying fibromas are benign asymptomatic neoplasms of the maxillae that generally have slow growth and present proliferation of fibrous cell tissue, with a varying quantity of bone products that include bone, cement or a combination of these. The cementoossifying fibroma is classified as a fibroosseous lesion of the jaws. Fibro osseous lesions classifications, pathophysiology and. Slow and progressive, cementoossifying fibroma is a rare benign tumor that reaches the maxilla and more frequently the mandible. Peripheral cemento ossifying fibroma in an adolescent. The term ossifying fibroma includes lesions with similar histological compositions and different forms of clinical behavior.
It is also compared with cemento ossifying fibroma which fcod resembles histopathologically 5. Indian j otolaryngol head neck surgjuly 2011 63 suppl 1. Peripheral cementoossifying fibroma in an adolescent. The establishment of the exact differentiation between cemento ossifying fibroma and fcod was made in 1971 7. It is difficult to differentiate the calcified tissue within the lesion between bone and cementum. It is usually located in the premolarmolar area in the mandible.
Fibroosseous lesions refer to a collection of nonneoplastic intraosseous lesions that replace normal bone and consist of a cellular fibrous connective tissue within which nonfunctional osseous structures form. Aug 28, 2019 cemento ossifying fibroma of the mandible. A case of cementoossifying fibroma involving the right side of mandible is described in a 38 yearold male patient, with description of clinical, radiographic, and histologic features. Cementoossifying fibroma of the mandible request pdf. Cherubism familial multilocular cystic disease of the jaws d. Pdf cementoossifying fibromas cofs are benign lesions affecting the jaws. Eversole fibro osseous lesions are a diverse group of processes that are characterized by replacement of. Cementoossifying fibroma is a benign osteogenic tumor with membranous ossification. Cemento ossifying fibroma presenting as a mass of the parapharyngeal and masticator space.
Peripheral cemento ossifying fibroma shows parakeratinised epithelium and well cellularised connective tissue containing mineralized components ranging from bone to cementum. Central cemento ossifying fibroma behaves like, a benign bone neoplasm. It causes swelling of the bone and sometimes creates a bowed leg. Cemento ossifying fibroma cof is considered a benign osseous tumour, very closely related to other lesions such as fibrous dysplasia, cementifying periapical dysplasia or amentoosseous dysplasia. Peripheral ossifying fibroma is a reactive lesion and peripheral odontogenic fibroma is an extraosseous variant of central odontogenic fibroma. Here we present a case of 18year old female having slow growing painless swelling on left side of mandible over 2year period. Cementoossifying fibroma is a rare benign tumor most often discovered incidentally. It is aggressive, locally destructive, and has a high. Cemento ossifying fibroma of mandible a case report. Cemento ossifying fibroma is a benign fibroosseous maxillary tumor belonging to the same category as fibrous dysplasia and. The other kind of ossifying fibroma, which grows in the leg bones, usually affects children in the first ten years of life.
A case report introduction fibromas are benign tumours arising from the connective tissue. Cemento ossifying fibroma is a rare benign tumor most often discovered incidentally. Cementoossifying fibroma radiology reference article. May 12, 2016 cemento ossifying fibroma is a benign growth, considered to originate from the periodontal ligament. Two cases of pof arising in the ethmoid sinus and involving the orbit are presented to emphasize the importance of complete surgical removal of involved bones. An extensive, destructive cementoossifying fibroma of the ethmoid region was found in a patient.
It commonly presents as a progressively growing lesion that can attain an. It is often encapsulated and predominantly located in the mandible, and presents as a slowgrowing lesion, but may cause deformity if left untreated. Cemento ossifying fibroma cof are rare, benign neoplasms that usually arise from the mandible or maxilla. Cementoossifying fibroma cof is a benign fibro osseous lesion of the jaws which has been described as a demarcated or rarely encapsulated neoplasm consisting of fibrous tissue and varying. Surgical enucleation with curettage of the lesion of the patient mentioned in this case report. The lesion over the time can cause facial asymmetry causing discomfort to the patient 2. Introduction cemento ossifying fibroma is a benign fibroosseous maxillary tumor belonging to the same category as fibrous dysplasia and cement ossifying dysplasia 1. She gave history of sudden onset, with lancinating type of pain which is severe in nature. Cystic cemento ossifying fibroma of the etmoidal cells a case report.
Cemento ossifying fibroma cof is a clinicopatological variant of ossifying fibroma which is benign fibroosseous neoplasm affecting jaw or cranial s. Cemento ossifying fibroma of the jaw dental jounal424 3. The ossifying and cementifying fibromas are differentiated by their clinical, radiological, and histological findings. Sep 01, 2019 cementifying fibroma definition of cementifying fibroma by medical dictionary s. Cementoossifying fibroma of the mandible sciencedirect. Terminology in the 2005 who histological classification of odontogeni. It therefore involves exclusively the maxillofacial bones 1, 2. Juvenile ossifying fibroma is a rare benign fibroosseous lesion. The diagnosis of cementoossifying fibroma of the jaw can be established based on clinical. However, in most cases both features are present, warranting the generic term cemento ossifying fibromas 1. They are included in the group of mesodermal odontogenic tumors.
Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. Cemento ossifying fibroma of the ethmoidal sinus manifesting as proptosis. Cementoossifying fibromas cofs are benign lesions affecting the jaws and other craniofacial bones. Two cases of multiple ossifying fibromas in the jaws pdf. Pediatric cementoossifying fibroma of the anterior. Cof is considered under fibroosseous lesion in who classification. Apr 19, 2011 we report a case of very large ossifying fibroma of the maxilla in a 22yearold male. Mandible maxilla benign tumors tumorlike conditions.
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